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Appl Environ Microbiol. 1964 May; 12(3): 195-196
Copyright © 1964 American Society for Microbiology. All Rights Reserved.

Influence of Inorganic Phosphorus on Oxytetracycline Formation by Streptomyces rimosus

Walter A. Zygmunt

Department of Microbiology & Natural Products Research, Mead Johnson Research Center, Mead Johnson & Company, Evansville, Indiana

ABSTRACT

Production of oxytetracycline by Streptomyces rimosus in several chemically defined media containing graded concentrations of inorganic phosphorus was studied in shake flasks. Although high levels of inorganic phosphate have been reported to inhibit oxytetracycline formation, this study indicated that composition of the medium is an important factor in determining whether antibiotic production will be stimulated or inhibited by specific concentrations of inorganic phosphate.

Appl Environ Microbiol. 1964 May; 12(3): 195-196
Copyright © 1964 American Society for Microbiology. All Rights Reserved.





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Copyright © 1964 by the American Society for Microbiology. All rights reserved.