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Appl Environ Microbiol. 1965 March; 13(2): 279-280
Copyright © 1965 American Society for Microbiology. All Rights Reserved.

Micromethod (Spot-Plate) Determination of In Vitro Antibiotic Susceptibility

Department of Pediatrics, Children's Memorial Hospital, University of Oklahoma Medical Center, Oklahoma City, Oklahoma

ABSTRACT

The spot-plate method for determining in vitro antibiotic susceptibility is a modified version of the standard tube dilution technique, with the same principle of twofold dilution. Results of the spot-plate method are compared with those of the standard tube dilution technique. It is proposed that the spot-plate method is an equally accurate, but more rapid and economical, technique for determining in vitro antibiotic susceptibility.