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Appl Environ Microbiol. 1967 May; 15(3): 566-568
Copyright © 1967 American Society for Microbiology. All Rights Reserved.

Activity of Selected Penicillins In Vitro and in Experimental Bacterial Infections in Mice

Gennaro J. Miraglia and Harold I. Basch

The Squibb Institute for Medical Research, New Brunswick, New Jersey

ABSTRACT

The minimal inhibitory concentration and the 50% mouse protective dose for five key penicillins are presented. Such data provide a useful guide in evaluating the activity of new penicillins, in comparison with those already commercially available, and establishes the amounts of antibiotic necessary to obtain a PD50 for several experimental model infections in mice.

Appl Environ Microbiol. 1967 May; 15(3): 566-568
Copyright © 1967 American Society for Microbiology. All Rights Reserved.





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Copyright © 1967 by the American Society for Microbiology. All rights reserved.