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Appl Environ Microbiol. 1967 July; 15(4): 733-735
Copyright © 1967 American Society for Microbiology. All Rights Reserved.

Inhibition of B Virus in Cell Culture by 5-Iodo-2'-Deoxyuridine

Francis A. Miller

Department of Microbiology, Parke, Davis & Company, Detroit, Michigan 48232

ABSTRACT

The antimetabolite 5-iodo 2'-deoxyuridine (IDU) interferes with B virus replication in monolayers of cynomolgous monkey kidney, KB and HEp 2 cells. To determine the effect of this clinically active nucleoside in laboratory antiviral screening systems, several methods were compared. Most of the methods used were capable of detecting the activity of IDU at low levels.

Appl Environ Microbiol. 1967 July; 15(4): 733-735
Copyright © 1967 American Society for Microbiology. All Rights Reserved.





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J. Bacteriol. Microbiol. Mol. Biol. Rev. Eukaryot. Cell All ASM Journals

Copyright © 1967 by the American Society for Microbiology. All rights reserved.