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Appl Environ Microbiol. 1967 September; 15(5): 1142-1144
Copyright © 1967 American Society for Microbiology. All Rights Reserved.

New Antibacterial Agent (U-24,544) Isolated from Streptomyces griseus

Ross R. Herr and Fritz Reusser

Department of Microbiology, The Upjohn Co., Kalamazoo, Michigan 49001

ABSTRACT

Antibiotic U-24,544 is a new agent isolated from the culture broth of a streptomycete strain. The antibiotic inhibits a variety of gram-positive and gram-negative bacteria in vitro, but is ineffective in treatment of experimental bacterial infections in mice. It is fairly cytotoxic in mammalian cell cultures and remarkably nontoxic in mice.

Appl Environ Microbiol. 1967 September; 15(5): 1142-1144
Copyright © 1967 American Society for Microbiology. All Rights Reserved.





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Copyright © 1967 by the American Society for Microbiology. All rights reserved.