This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Mandal, A. Articles by Majumdar, S. K. Search for Related Content PubMed Articles by Mandal, A. Articles by Majumdar, S. K. Agricola Articles by Mandal, A. Articles by Majumdar, S. K.

 Previous Article  |  Next Article 

Appl Environ Microbiol. 1968 November; 16(11): 1786-1789
Copyright © 1968 American Society for Microbiology. All Rights Reserved.

Effect of Streptomycin on Some Enzyme Systems of Bacillus subtilis

Department of Biochemistry, University College of Science, Calcutta 19, India

ABSTRACT

Streptomycin slightly inhibited lactic and malic dehydrogenases of Bacillus subtilis, and inhibited isocitric dehydrogenase to about 60%. The formation of lactic dehydrogenase, glutamic dehydrogenase, -alanine dehydrogenase, and succinic dehydrogenase was stimulated by the antibiotic at a concentration causing 50% inhibition of bacterial growth. Streptomycin had practically no influence on the formation of malic dehydrogenase, but the antibiotic produced 48% inhibition of the synthesis of isocitric dehydrogenase.

¹ Present address: Department of Food Technology and Biochemical Engineering, Jadavpur University, Calcutta 32, India.