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Appl Environ Microbiol. 1969 May; 17(5): 707-709
Copyright © 1969 American Society for Microbiology. All Rights Reserved.

Tube Dilution Antimicrobial Susceptibility Testing: Efficacy of a Microtechnique Applicable to Diagnostic Laboratories

¹ Department of Pediatrics, Children's Memorial Hospital, University of Oklahoma Medical Center, Oklahoma City, Oklahoma 73104

ABSTRACT

A microtechnique for determining antibiotic susceptibilities by the serial dilution method was evaluated in a clinical diagnostic microbiology laboratory. As compared with the standard tube method, an agreement of 94% was achieved for determining minimal inhibitory concentration with ± one tube dilution as the criterion of comparison. The experience with this system suggests that it could easily be incorporated into diagnostic laboratories as a routine procedure.