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Appl Environ Microbiol. 1969 June; 17(6): 830-835
Copyright © 1969 American Society for Microbiology. All Rights Reserved.

Stabilities of Dried Suspensions of Influenza Virus Sealed in a Vacuum or Under Different Gases

Department of Pathology, Marquette School of Medicine, Inc., Milwauke, Wisconsin 53233
Department of Pathology, Baptist Memorial Hospital, Memphis, Tennessee 38103
Department of Microbiology, University of Tennessee School of Basic Medical Sciences, Memphis, Tennessee 38103

ABSTRACT

Suspensions of purified influenza virus, dried to a 1.4% content of residual moisture by sublimation of ice in vacuo, were sealed in a vacuum or under different gases of high purity. The stabilities of the several preparations were determined by an accelerated storage test. Based on the times predicted for the dried preparations stored at different temperatures to lose 1 log of infectivity titer, the order of stabilities in relation to sealing in vacuum or under different gases was as follows: helium > hydrogen > vacuum > argon > nitrogen > oxygen > carbon dioxide.