AEM
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Doupnik, B.
Right arrow Articles by Peckham, J. C.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Doupnik, B., Jr.
Right arrow Articles by Peckham, J. C.
Agricola
Right arrow Articles by Doupnik, B.
Right arrow Articles by Peckham, J. C.

 Previous Article  |  Next Article 

Appl Environ Microbiol. 1970 April; 19(4): 594-597
Copyright © 1970 American Society for Microbiology. All Rights Reserved.

Mycotoxicity of Aspergillus ochraceus to Chicks 1

Ben Doupnik Jr. and John C. Peckham

University of Georgia Coastal Plain Experiment Station and Diagnostic and Research Laboratories, University of Georgia School of Veterinary Medicine, Tifton, Georgia 31794

ABSTRACT

Five isolates of Aspergillus ochraceus, obtained from peanuts, were grown separately on sterile, moist corn for 14 days and fed to 1-day-old Babcock B-300 cockerels to evaluate their toxic effects. Two isolates were highly toxic, causing death of all birds during the 1st week of the experiment. Two isolates were moderately toxic, causing severe growth suppression with some deaths occurring throughout the 3-week test period. One isolate had no apparent effect. When the two most toxic isolates (diets) were diluted, survival time increased but severe growth suppression was evident. Postmortem examinations revealed a few small hemorrhages in the proventriculi of birds which died between the 2nd and 5th days. Emaciation, dehydration, and dry, firm gizzard linings were observed throughout the experiment. Extensive hepatic injury consisting of either fatty changes or necrotic foci was the principal microscopic finding. Suppression of bone marrow activity and depletion of lymphoid elements in the spleen and bursa of Fabricius were also found. The severity of the histopathological changes was directly related to the concentration of ochratoxin A in the diets.

FOOTNOTES

1 Published as University of Georgia Experiment Stations Journal Series Paper 659 and Institute of Comparative Medicine Manuscript 757.

Appl Environ Microbiol. 1970 April; 19(4): 594-597
Copyright © 1970 American Society for Microbiology. All Rights Reserved.





Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
J. Bacteriol. Microbiol. Mol. Biol. Rev. Eukaryot. Cell All ASM Journals

Copyright © 1970 by the American Society for Microbiology. All rights reserved.