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Appl Environ Microbiol. 1970 April; 19(4): 621-623
Copyright © 1970 American Society for Microbiology. All Rights Reserved.

Automated Microtitration Test for Antistreptolysin O ¹

Provincial Laboratory of Public Health, The University of Alberta, Edmonton, Alberta, Canada

ABSTRACT

A commercially available instrument that automatically makes serial dilutions and delivers reagents was used for the determination of antistreptolysin O titers in serum. The automated method was compared with tube-dilution and manual microtitration techniques. It gave higher reproducibility of results and was quicker to perform than both the other tests; and it was much more economical in reagents than the tube test. The automated technique is considered to be the best of the three methods when more than a small number of specimens are examined at one time. It is now in routine use in our laboratory.

¹ Presented in part at the 37th Annual Meeting of the Laboratory Section of the Canadian Public Health Association held in Toronto, Ontario, November 1969.