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Appl Environ Microbiol. 1970 December; 20(6): 984-985
Copyright © 1970 American Society for Microbiology. All Rights Reserved.

Improved Device for the Administration of Fungal Spores to Small Animals via the Respiratory Route

Department of Microbiology, West Virginia University Medical Center, Morgantown, West Virginia 26506

ABSTRACT

An improved device has been designed and constructed for the administration of fungal spores or other air-suspended particles to mice via inhalation. Fabricated from Lucite [0.25 inch (0.63 cm)], the device was built in the shape of a 6-inch (15.2-cm) cube with two 1-inch (2.5-cm) holes drilled in each side. Mice are restrained in plastic conical centrifuge tubes which fit into the holes by friction. The device is safe, easily cleaned and sterilized, and can accommodate up to eight animals at a single exposure.