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Appl Environ Microbiol. 1971 February; 21(2): 244-252
Copyright © 1971 American Society for Microbiology. All Rights Reserved.
Naval Biomedical Research Laboratory, School of Public Health, University of California, Berkeley, California 94720
ABSTRACT
Mathematical considerations of the behavior of aerosolized particles in a rotating drum are presented, and the rotating drum as an aerosol-holding device is compared with a stirred settling chamber. The basic overall design elements of a facility employing eight rotating drums are presented. This facility provides an environment in which temperature can be maintained within 0.5 F (0.25 C) of any set point over a range of 50 to 120 F (10 to 49 C); concomitantly the relative humidity within any selected drum may be controlled in a nominal range of 0 to 90%. Some of the major technical aspects of operating this facility are also presented, including handling of air support systems, aerosol production, animal exposure, aerosol monitoring, and sampling.
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