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Appl Environ Microbiol. 1971 February; 21(2): 257-259
Copyright © 1971 American Society for Microbiology. All Rights Reserved.

Comparison of the Streptozyme Test with the Antistreptolysin O, Antideoxyribonuclease B, and Antihyaluronidase Tests

Bacterial Immunology Unit, Center for Disease Control, Atlanta, Georgia 30333

ABSTRACT

The streptozyme test was compared with the antistreptolysin O (ASO), antideoxyribonuclease B (ADN-B), and antihyaluronidase (AH) tests. One hundred and twenty-seven human serum specimens were tested by each of the four tests. The streptozyme test detected more specimens with elevated titers than any single test; however, it was not as effective as the combination of the ASO and ADN-B tests. The streptozyme test appears to be particularly useful for laboratories which rely solely on the ASO test for serological evidence of a streptococcal infection. The test can be used in these laboratories to screen all specimens with low ASO titers (<170) for the detection of ADN, AH, antinicotinamide adenine dinucleotidase, and antistreptokinase.