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Appl Environ Microbiol. 1971 December; 22(6): 1096-1099
Copyright © 1971 American Society for Microbiology. All Rights Reserved.

Effect of Newcastle Disease on Serum Copper, Zinc, Cholesterol, and Carotenoid Values in the Chick

Rutgers, The State University, New Brunswick, New Jersey 08903
U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland 21701

ABSTRACT

Experimentally induced Newcastle disease virus infection of chicks, with a mortality index of 48%, was accompanied by increased concentrations in serum of copper and cholesterol and decreased concentrations of zinc and total carotenoids. These changes distorted, or were superimposed upon, the rhythmic variability in the normal serum concentrations of each of these moieties. Changing values for copper, zinc, and cholesterol became apparent before any overt signs of disease.