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Appl Environ Microbiol. 1971 December; 22(6): 1162-1163
Copyright © 1971 American Society for Microbiology. All Rights Reserved.

Effect of Polycations on Sensitivity of BALB/3T3 Cells to Murine Leukemia and Sarcoma Virus Infectivity

Jarue S. Manning1, Adeline J. Hackett and Norman B. Darby Jr.2

Cell Culture Laboratory, Naval Biomedical Research Laboratory, School of Public Health, University of California, Berkeley, California 94625

ABSTRACT

Polybrene or diethylaminoethyl dextran, when added with murine leukemia or sarcoma virus inocula, significantly increased virus infectivity of BALB/3T3 cells. Residual polycation concentrations were nontoxic.

FOOTNOTES

1 Present address: Department of Veterinary Microbiology, School of Veterinary Medicine, University of California Davis, Calif. 95616.

2 Present address: Comparative Oncology Laboratory, University of California, Davis, Calif. 95616.

Appl Environ Microbiol. 1971 December; 22(6): 1162-1163
Copyright © 1971 American Society for Microbiology. All Rights Reserved.





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Copyright © 1971 by the American Society for Microbiology. All rights reserved.