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Appl Environ Microbiol. 1972 August; 24(2): 202-204
Copyright © 1972 American Society for Microbiology. All Rights Reserved.

Comparison of the Reliability and Sensitivity of Three Serological Procedures in Detecting Antibody to Yersinia pestis (Pasteurella pestis)

Microbiology Division, U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland 21701
Microbiology Division, Biological Defense Research Laboratory, Fort Detrick, Maryland 21701
Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Washington, D.C. 20012

ABSTRACT

Three serological procedures, the agar-gel precipitin inhibition, the complement fixation, and the indirect hemagglutination tests, were used to detect and measure antibody to Yersinia pestis in the sera from 383 individuals. Although all three tests were useful in detecting plague antibody, the most reliable and sensitive test procedure was indirect hemagglutination.