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Appl Environ Microbiol. 1973 July; 26(1): 56-58
Copyright © 1973 American Society for Microbiology. All Rights Reserved.

Evaluation of Streptozyme and Antistreptolysin O Tests in Streptococcal Pyodermal Nephritis

Unit for Prevention of Cross-Infection in Hospitals, National Streptococcus Reference Laboratory, Government Central Laboratories, Ministry of Health, Jerusalem, Israel
Laboratory for Microbiology and Immunology, Faculty of Dental Medicine, The Hebrew University Alpha Omega Research and Postgraduate Center, Jerusalem, Israel

ABSTRACT

The evaluation of the streptozyme test in sera from 34 patients with streptococcal pyodermal nephritis was studied. Ninety-seven percent of the patients developed high titers of antistreptozyme antibodies on the first bleeding after hospitalization, in contrast to only 40% of patients who developed elevated antistreptolysin O titers. The high antistreptozyme titers declined during convalescence and reached normal levels in the sixth month after onset of the disease. The most significant fall in titers occurred between 1 and 2 months from the onset of disease. The streptozyme test may be particularly helpful as a rapid screening test for antibodies in streptococcal pyodermal nephritis.