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Appl Environ Microbiol. 1973 September; 26(3): 264-267
Copyright © 1973 American Society for Microbiology. All Rights Reserved.

Suppression of Herpes Simplex Virus Infection by Phosphonoacetic Acid

N. L. Shipkowitz, R. R. Bower, R. N. Appell, C. W. Nordeen, L. R. Overby, W. R. Roderick, J. B. Schleicher and A. M. Von Esch

Abbott Laboratories, North Chicago, Illinois 60064

ABSTRACT

Disodium phosphonoacetate when administered orally or topically to mice experimentally infected with herpes simplex virus was able to significantly reduce the mortality associated with the agent. In addition, this compound was able to reduce herpesvirus lesions on the corneas of infected rabbits.


Appl Environ Microbiol. 1973 September; 26(3): 264-267
Copyright © 1973 American Society for Microbiology. All Rights Reserved.







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Copyright © 1973 by the American Society for Microbiology. All rights reserved.