This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Lanzilotta, R. P. Articles by McDonald, K. M. Search for Related Content PubMed Articles by Lanzilotta, R. P. Articles by McDonald, K. M. Agricola Articles by Lanzilotta, R. P. Articles by McDonald, K. M.

 Previous Article  |  Next Article 

Appl Environ Microbiol. 1974 January; 27(1): 130-134
Copyright © 1974 American Society for Microbiology. All Rights Reserved.

Microbial Reduction of Ketopantoyl Lactone to Pantoyl Lactone¹

^a Institute of Organic Chemistry, Syntex Research, Palo Alto, California 94304

ABSTRACT

The results of a microbial survey study have shown that the ability to reduce added ketopantoic acid (or ketopantoyl lactone) and accumulate pantoic acid (or pantoyl lactone) in the growth medium is widespread among diverse fungi. The reductions generally proceeded with less than full stereoselectivity. However, specific strains of the ascomycete Byssochlamys fulva were found to form D[-]-pantoic acid in unusually high yields and optical purity.

¹ Contribution no. 409 from the Institute of Organic Chemistry.