This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Teh, J. S. Search for Related Content PubMed Articles by Teh, J. S. Agricola Articles by Teh, J. S.

 Previous Article  |  Next Article 

Appl Environ Microbiol. 1974 November; 28(5): 840-844
Copyright © 1974 American Society for Microbiology. All Rights Reserved.

Toxicity of Short-Chain Fatty Acids and Alcohols Towards Cladosporium resinae

Department of Biochemistry, Faculty of Medicine, University of Singapore, Singapore 3

ABSTRACT

Long-chain saturated fatty acids (C₁₃ to C₁₈) and fatty alcohols (C₁₂ to C₁₈) were well utilized by three different soil isolates of Cladosporium resinae as the sole carbon and energy sources in static liquid cultures. Shorter-chain compounds, down to C₅, did not support growth and were in fact toxic towards the fungus growing on glucose. Rapid and considerable potassium efflux, protein leakage, and inhibition of endogenous respiration were observed in the presence of the shorter fatty acids and alcohols. Possible mechanisms and significance of the toxicity are discussed.