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Appl Environ Microbiol. 1974 December; 28(6): 1033-1039
Copyright © 1975 American Society for Microbiology. All Rights Reserved.

Ecological Application of Antibiotics as Respiratory Inhibitors of Bacterial Populations¹

Department of Microbiology, University of Georgia, Athens, Georgia 30602

ABSTRACT

Two terregenous and four marine bacterial isolates were treated with six antibiotics and antibiotic combinations. Comparisons made between responses of cells in early and late logarithmic and stationary growth phases indicated variable sensitivity to the agents. Bacteria in stationary and late log-phase cultures exhibited the greatest resistance, whereas the early log-phase cells exhibited greatest antibiotic susceptibility. We conclude that the tested antibiotics cannot be used for ecological purposes to delineate bacterial respiration in mixed microbial communities.

¹ Contribution no. 284 from the University of Georgia Marine Institute, Sapelo Island, Ga.