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Appl Environ Microbiol. 1978 February; 35(2): 459-461

Tryptophan excretion by a bradytroph of Hansenula polymorpha growing in methanol.

S Sanchez and A L Demain

ABSTRACT

The growth of a bradytrophic mutant isolated from the methanol-utilizing yeast Hansenula polymorpha was found to be stimulated by both tyrosine and phenylalanine. The mutant contained about half as much chorismate mutase activity as the wild-type strain. When grown in a medium containing 2% mehtanol as the major carbon and energy source, the bradytroph excreted a low but significant level (28 mg/liter) of L-tryptophan.

Appl Environ Microbiol. 1978 February; 35(2): 459-461






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