This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Rutqvist, L Articles by Carlsson, B Search for Related Content PubMed PubMed Citation Articles by Rutqvist, L Articles by Carlsson, B Agricola Articles by Rutqvist, L Articles by Carlsson, B

 Previous Article  |  Next Article 

Appl Environ Microbiol. 1978 December; 36(6): 920-925

Ochratoxin A as the cause of spontaneous nephropathy in fattening pigs.

ABSTRACT

At a number of slaughters nephropathy and high ochratoxin A contents in kidneys have been observed in fattening pigs from two Swedish farms. In one herd the source of contamination was barley grown on the home farm and stored under such conditions that the growth of fungal species (Penicillium verrucosum var. verrucosum) producing ochratoxin A occurred, with the subsequent formation of the toxin. In this case high ochratoxin A levels in fattening pigs were found during a period of about 18 months. In the second herd, where compounded feed was used, it was impossible to locate the source of contamination. It was presumed that a consignment of feed was damaged by rain during storage at the farm. Ochratoxin A was found in fattening pigs from this herd for a period of about 2 months. Ochratoxin A appeared in the kidneys of all investigated pigs. In some animals the livers, whole blood, and plasma were analyzed, too. The livers contained somewhat lower amounts of ochratoxin A than the kidneys, whereas the content in whole blood and plasma, respectively, was 5 and 13 times greater. Kidneys spontaneously contaminated with ochratoxin A, when stored for 10 months at -70 degrees C, showed no systematic decrease in toxin content.

This article has been cited by other articles:

• Bennett, J. W., Klich, M. (2003). Mycotoxins. Clin. Microbiol. Rev. 16: 497-516 [Abstract] [Full Text]  
• Novotny, W. E., Dixit, A. (2000). Pulmonary Hemorrhage in an Infant Following 2 Weeks of Fungal Exposure. Arch Pediatr Adolesc Med 154: 271-275 [Abstract] [Full Text]