This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Murray, J P Articles by Laband, S J Search for Related Content PubMed PubMed Citation Articles by Murray, J P Articles by Laband, S J Agricola Articles by Murray, J P Articles by Laband, S J

 Previous Article  |  Next Article 

Appl Environ Microbiol. 1979 March; 37(3): 480-486

Degradation of poliovirus by adsorption on inorganic surfaces.

ABSTRACT

Alteration of the specific infectivity of 3H-labeled ribonucleic acid and 14C-protein labeled poliovirus type 1 by adsorption on inorganic surfaces is investigated by application of kinetic theory to data obtained from sequential extractions of adsorbed virus. Some surfaces, e.g., SiO2, appear to have no significant effect. On the other hand, CuO substantially decreases the specific infectivity of adsorbed preparations. Differences in kinetic plots between 3H-labeled ribonucleic acid and 14C-labeled protein suggest that the inactivation observed involves physical disruption of virions. Van der Waals interactions between solid surfaces and virus are suspected to induce spontaneous virion disassembly. Surface catalyzed disassembly in aquatic and soil environments is implicated as an important mechanism controlling enterovirus dissemination. Methods developed here to evaluate complete recovery of adsorbed virus have potenital application to other degradation studied and problems concerning virus recovery from adsorbents used in virus concentrators.

This article has been cited by other articles:

• Monpoeho, S., Maul, A., Bonnin, C., Patria, L., Ranarijaona, S., Billaudel, S., Ferre, V. (2004). Clearance of Human-Pathogenic Viruses from Sludge: Study of Four Stabilization Processes by Real-Time Reverse Transcription-PCR and Cell Culture. Appl. Environ. Microbiol. 70: 5434-5440 [Abstract] [Full Text]  
• Chu, Y., Jin, Y., Baumann, T., Yates, M. V. (2003). Effect of Soil Properties on Saturated and Unsaturated Virus Transport through Columns. J. Environ. Qual. 32: 2017-2025 [Abstract] [Full Text]