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Appl Environ Microbiol. 1979 November; 38(5): 836-839

N-demethylation of nicotine and reduction of nicotine-1'-N-oxide by Microsporum gypseum.

R D Sindelar, J P Rosazza and C F Barfknecht

ABSTRACT

Several microorganisms were examined for their abilities to convert S-nicotine into nornicotine. Five microorganisms including Microsporum gypseum (ATCC 11395) produced nornicotine and three unknown metabolites. M. gypseum efficiently reduced nicotine-1'-N-oxide to nicotine, but no nornicotine was obtained when the N-oxide was used as substrate.

Appl Environ Microbiol. 1979 November; 38(5): 836-839






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