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Appl Environ Microbiol. 1985 April; 49(4): 842-845

Kinetic profiles of diacetoxyscirpenol and two of its metabolites in blood serum of pigs.

J Bauer, W Bollwahn, M Gareis, B Gedek and K Heinritzi

ABSTRACT

Orally administered diacetoxyscirpenol (2 mg/kg of body weight) was rapidly absorbed into the blood serum of pigs; within 1 h, the highest amounts of diacetoxyscirpenol (9.6 to 21.9 ng/ml) were detected. Two metabolites of diacetoxyscirpenol were identified by gas chromatography-mass spectroscopy as monoacetoxyscirpenol and scirpenetriol. The three trichothecenes were present in the blood serum of pigs for only 24 h, indicating a rapid metabolism of these compounds.

Appl Environ Microbiol. 1985 April; 49(4): 842-845






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