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Appl Environ Microbiol. 1985 July; 50(1): 179-182
Copyright © 1985, American Society for Microbiology. All Rights Reserved.
Department of Microbiology and Immunology, Queen's University, Kingston, Ontario, Canada K7L 3N6
ABSTRACT
Methanogenesis by Methanobacterium thermoautotrophicum strains was extremely sensitive to gramicidin, total inhibition being observed at 0.2 µg/ml. In contrast, methane synthesis by Methanococcus voltae, Methanogenium marisnigri, Methanosarcina mazei, and Methanospirillum hungatei were resistant to the highest concentrations of gramicidin tested (40 µg/ml), although spheroplasts of Methanospirillum hungatei were extremely sensitive. Other species tested showed intermediate sensitivity to gramicidin, methanogenesis inhibition occurring at 4 to 20 µg/ml.
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