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Appl Environ Microbiol. 1985 November; 50(5): 1238-1243

Isolation and characterization of butanol-resistant mutants of Clostridium acetobutylicum.

M Hermann, F Fayolle, R Marchal, L Podvin, M Sebald and J P Vandecasteele

ABSTRACT

In a wild-type strain of Clostridium acetobutylicum isolated from soil, solvent production appeared limited by butanol toxicity. Butanol-resistant mutants have been obtained which produced significantly higher solvent concentrations (about 30%) than the wild-type strain. Some other physiological differences were observed between a selected resistant mutant and the wild-type strain at the level of solvent resistance and sporulation.

Appl Environ Microbiol. 1985 November; 50(5): 1238-1243






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