This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Sawant, A D Articles by Ahearn, D G Search for Related Content PubMed PubMed Citation Articles by Sawant, A D Articles by Ahearn, D G Agricola Articles by Sawant, A D Articles by Ahearn, D G

 Previous Article  |  Next Article 

Appl Environ Microbiol. 1988 May; 54(5): 1099-1103

Anti-Candida albicans activity of Pichia anomala as determined by a growth rate reduction assay.

Laboratory for Microbial and Biochemical Sciences, Georgia State University, Atlanta 30303.

ABSTRACT

Killer toxin activity of Pichia anomala WC65 appeared fungicidal for P. bimundalis WC38 and fungistatic for Candida albicans RC1. Inhibitory activity against sensitive C. albicans showed a linear relationship between toxin concentrations and the inverse of the reduced growth rates. The plot of toxin concentrations against growth rates was hyperbolic, as is characteristic of saturation kinetics. Sensitivity of C. albicans to the toxin decreased with increased cell age. The measurement of growth rate reduction provided a simple and accurate method for quantitation of toxin.

This article has been cited by other articles:

• Ciani, M., Fatichenti, F. (2001). Killer Toxin of Kluyveromyces phaffii DBVPG 6076 as a Biopreservative Agent To Control Apiculate Wine Yeasts. Appl. Environ. Microbiol. 67: 3058-3063 [Abstract] [Full Text]