This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kurtenbach, K.
Right arrow Articles by Randolph, S. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kurtenbach, K.
Right arrow Articles by Randolph, S. E.
Agricola
Right arrow Articles by Kurtenbach, K.
Right arrow Articles by Randolph, S. E.

Next Article 

Appl Environ Microbiol, April 1998, p. 1169-1174, Vol. 64, No. 4
0099-2240/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Differential Transmission of the Genospecies of Borrelia burgdorferi Sensu Lato by Game Birds and Small Rodents in England

Klaus Kurtenbach,1,2,* Mick Peacey,1,2 Sjoerd G. T. Rijpkema,3,dagger Andrew N. Hoodless,1,4 Patricia A. Nuttall,2 and Sarah E. Randolph1

Department of Zoology, University of Oxford, OX1 3PS, Oxford,1 NERC Institute of Virology and Environmental Microbiology, OX1 3SR, Oxford,2 and The Game Conservancy Trust, Fordingbridge, SP6 1EF, Hampshire,4 United Kingdom, and Research Laboratory for Infectious Diseases, National Institute of Public Health and the Environment, 3720BA, Bilthoven, The Netherlands3

Received 24 September 1997/Accepted 1 January 1998

The genetic diversity of Borrelia burgdorferi sensu lato was assessed in a focus of Lyme borreliosis in southern Britain dominated by game birds. Ticks, rodents, and pheasants were analyzed for spirochete infections by PCR targeting the 23S-5S rRNA genes, followed by genotyping by the reverse line blot method. In questing Ixodes ricinus ticks, three genospecies of B. burgdorferi sensu lato were detected, with the highest prevalences found for Borrelia garinii and Borrelia valaisiana. B. burgdorferi sensu stricto was rare (<1%) in all tick stages. Borrelia afzelii was not detected in any of the samples. More than 50% of engorged nymphs collected from pheasants were infected with borreliae, mainly B. garinii and/or B. valaisiana. Although 19% of the rodents harbored B. burgdorferi sensu stricto and/or B. garinii in internal organs, only B. burgdorferi sensu stricto was transmitted to xenodiagnostic tick larvae (it was transmitted to 1% of the larvae). The data indicate that different genospecies of B. burgdorferi sensu lato can be maintained in nature by distinct transmission cycles involving the same vector tick species but different vertebrate host species. Wildlife management may have an influence on the relative risk of different clinical forms of Lyme borreliosis.

* Corresponding author. Mailing address: The Wellcome Trust Center for the Epidemiology of Infectious Diseases, Department of Zoology, University of Oxford, OX1 3PS, Oxford, United Kingdom. Phone: 0044-1865-281630. Fax: 0044-1865-281696. E-mail: kku{at}mail.nerc-oxford.ac.uk.

dagger Present address: National Institute of Biological Standards and Controls, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, United Kingdom.




This article has been cited by other articles:

  • Margos, G., Vollmer, S. A., Cornet, M., Garnier, M., Fingerle, V., Wilske, B., Bormane, A., Vitorino, L., Collares-Pereira, M., Drancourt, M., Kurtenbach, K. (2009). A New Borrelia Species Defined by Multilocus Sequence Analysis of Housekeeping Genes. Appl. Environ. Microbiol. 75: 5410-5416 [Abstract] [Full Text]  
  • Dubska, L., Literak, I., Kocianova, E., Taragelova, V., Sychra, O. (2009). Differential Role of Passerine Birds in Distribution of Borrelia Spirochetes, Based on Data from Ticks Collected from Birds during the Postbreeding Migration Period in Central Europe. Appl. Environ. Microbiol. 75: 596-602 [Abstract] [Full Text]  
  • Staszewski, V, McCoy, K.D, Boulinier, T (2008). Variable exposure and immunological response to Lyme disease Borrelia among North Atlantic seabird species. Proc R Soc B 275: 2101-2109 [Abstract] [Full Text]  
  • Chu, C.-Y., Jiang, B.-G., Liu, W., Zhao, Q.-M., Wu, X.-M., Zhang, P.-H., Zhan, L., Yang, H., Cao, W.-C. (2008). Presence of pathogenic Borrelia burgdorferi sensu lato in ticks and rodents in Zhejiang, south-east China. J Med Microbiol 57: 980-985 [Abstract] [Full Text]  
  • Ladbury, G. A. F., Stuen, S., Thomas, R., Bown, K. J., Woldehiwet, Z., Granquist, E. G., Bergstrom, K., Birtles, R. J. (2008). Dynamic Transmission of Numerous Anaplasma phagocytophilum Genotypes among Lambs in an Infected Sheep Flock in an Area of Anaplasmosis Endemicity. J. Clin. Microbiol. 46: 1686-1691 [Abstract] [Full Text]  
  • Taragel'ova, V., Koci, J., Hanincova, K., Kurtenbach, K., Derdakova, M., Ogden, N. H., Literak, I., Kocianova, E., Labuda, M. (2008). Blackbirds and Song Thrushes Constitute a Key Reservoir of Borrelia garinii, the Causative Agent of Borreliosis in Central Europe. Appl. Environ. Microbiol. 74: 1289-1293 [Abstract] [Full Text]  
  • Bown, K. J., Lambin, X., Ogden, N. H., Petrovec, M., Shaw, S. E., Woldehiwet, Z., Birtles, R. J. (2007). High-Resolution Genetic Fingerprinting of European Strains of Anaplasma phagocytophilum by Use of Multilocus Variable-Number Tandem-Repeat Analysis. J. Clin. Microbiol. 45: 1771-1776 [Abstract] [Full Text]  
  • Poupon, M.-A., Lommano, E., Humair, P.-F., Douet, V., Rais, O., Schaad, M., Jenni, L., Gern, L. (2006). Prevalence of Borrelia burgdorferi Sensu Lato in Ticks Collected from Migratory Birds in Switzerland. Appl. Environ. Microbiol. 72: 976-979 [Abstract] [Full Text]  
  • Rauter, C., Hartung, T. (2005). Prevalence of Borrelia burgdorferi Sensu Lato Genospecies in Ixodes ricinus Ticks in Europe: a Metaanalysis. Appl. Environ. Microbiol. 71: 7203-7216 [Abstract] [Full Text]  
  • Gil, H., Barral, M., Escudero, R., Garcia-Perez, A. L., Anda, P. (2005). Identification of a New Borrelia Species among Small Mammals in Areas of Northern Spain Where Lyme Disease Is Endemic. Appl. Environ. Microbiol. 71: 1336-1345 [Abstract] [Full Text]  
  • Richter, D., Schlee, D. B., Allgower, R., Matuschka, F.-R. (2004). Relationships of a Novel Lyme Disease Spirochete, Borrelia spielmani sp. nov., with Its Hosts in Central Europe. Appl. Environ. Microbiol. 70: 6414-6419 [Abstract] [Full Text]  
  • Derdakova, M., Dudioak, V., Brei, B., Brownstein, J. S., Schwartz, I., Fish, D. (2004). Interaction and Transmission of Two Borrelia burgdorferi Sensu Stricto Strains in a Tick-Rodent Maintenance System. Appl. Environ. Microbiol. 70: 6783-6788 [Abstract] [Full Text]  
  • Masuzawa, T., Hashimoto, N., Kudeken, M., Kadosaka, T., Nakamura, M., Kawabata, H., Koizumi, N., Imai, Y. (2004). New genomospecies related to Borrelia valaisiana, isolated from mammals in Okinawa archipelago, Japan. J Med Microbiol 53: 421-426 [Abstract] [Full Text]  
  • Richter, D., Klug, B., Spielman, A., Matuschka, F.-R. (2004). Adaptation of Diverse Lyme Disease Spirochetes in a Natural Rodent Reservoir Host. Infect. Immun. 72: 2442-2444 [Abstract] [Full Text]  
  • Kampen, H., Rotzel, D. C., Kurtenbach, K., Maier, W. A., Seitz, H. M. (2004). Substantial Rise in the Prevalence of Lyme Borreliosis Spirochetes in a Region of Western Germany over a 10-Year Period. Appl. Environ. Microbiol. 70: 1576-1582 [Abstract] [Full Text]  
  • Collares-Pereira, M., Couceiro, S., Franca, I., Kurtenbach, K., Schafer, S. M., Vitorino, L., Goncalves, L., Baptista, S., Vieira, M. L., Cunha, C. (2004). First Isolation of Borrelia lusitaniae from a Human Patient. J. Clin. Microbiol. 42: 1316-1318 [Abstract] [Full Text]  
  • Guner, E. S., Hashimoto, N., Takada, N., Kaneda, K., Imai, Y., Masuzawa, T. (2003). First isolation and characterization of Borrelia burgdorferi sensu lato strains from Ixodes ricinus ticks in Turkey. J Med Microbiol 52: 807-813 [Abstract] [Full Text]  
  • Hanincova, K., Taragelova, V., Koci, J., Schafer, S. M., Hails, R., Ullmann, A. J., Piesman, J., Labuda, M., Kurtenbach, K. (2003). Association of Borrelia garinii and B. valaisiana with Songbirds in Slovakia. Appl. Environ. Microbiol. 69: 2825-2830 [Abstract] [Full Text]  
  • Etti, S., Hails, R., Schafer, S. M., De Michelis, S., Sewell, H.-S., Bormane, A., Donaghy, M., Kurtenbach, K. (2003). Habitat-Specific Diversity of Borrelia burgdorferi Sensu Lato in Europe, Exemplified by Data from Latvia. Appl. Environ. Microbiol. 69: 3008-3010 [Abstract] [Full Text]  
  • Ogden, N. H., Casey, A. N. J., Woldehiwet, Z., French, N. P. (2003). Transmission of Anaplasma phagocytophilum to Ixodes ricinus Ticks from Sheep in the Acute and Post-Acute Phases of Infection. Infect. Immun. 71: 2071-2078 [Abstract] [Full Text]  
  • Derdakova, M., Beati, L., Pet'ko, B., Stanko, M., Fish, D. (2003). Genetic Variability within Borrelia burgdorferi Sensu Lato Genospecies Established by PCR-Single-Strand Conformation Polymorphism Analysis of the rrfA-rrlB Intergenic Spacer in Ixodes ricinus Ticks from the Czech Republic. Appl. Environ. Microbiol. 69: 509-516 [Abstract] [Full Text]  
  • Kurtenbach, K., Schafer, S. M., Sewell, H.-S., Peacey, M., Hoodless, A., Nuttall, P. A., Randolph, S. E. (2002). Differential Survival of Lyme Borreliosis Spirochetes in Ticks That Feed on Birds. Infect. Immun. 70: 5893-5895 [Abstract] [Full Text]  
  • Qiu, W.-G., Dykhuizen, D. E., Acosta, M. S., Luft, B. J. (2002). Geographic Uniformity of the Lyme Disease Spirochete (Borrelia burgdorferi) and Its Shared History With Tick Vector (Ixodes scapularis) in the Northeastern United States. Genetics 160: 833-849 [Abstract] [Full Text]  
  • Kurtenbach, K., De Michelis, S., Sewell, H.-S., Etti, S., Schafer, S. M., Hails, R., Collares-Pereira, M., Santos-Reis, M., Hanincova, K., Labuda, M., Bormane, A., Donaghy, M. (2001). Distinct Combinations of Borrelia burgdorferi Sensu Lato Genospecies Found in Individual Questing Ticks from Europe. Appl. Environ. Microbiol. 67: 4926-4929 [Abstract] [Full Text]  
  • Hammer, B., Moter, A., Kahl, O., Alberti, G., Gobel, U. B. (2001). Visualization of Borrelia burgdorferi sensu lato by fluorescence in situ hybridization (FISH) on whole-body sections of Ixodes ricinus ticks and gerbil skin biopsies. Microbiology 147: 1425-1436 [Abstract] [Full Text]  
  • Escudero, R., Barral, M., Pérez, A., Vitutia, M. M., García-Pérez, A. L., Jiménez, S., Sellek, R. E., Anda, P. (2000). Molecular and Pathogenic Characterization of Borrelia burgdorferi Sensu Lato Isolates from Spain. J. Clin. Microbiol. 38: 4026-4033 [Abstract] [Full Text]  
  • De Michelis, S., Sewell, H.-S., Collares-Pereira, M., Santos-Reis, M., Schouls, L. M., Benes, V., Holmes, E. C., Kurtenbach, K. (2000). Genetic Diversity of Borrelia burgdorferi Sensu Lato in Ticks from Mainland Portugal. J. Clin. Microbiol. 38: 2128-2133 [Abstract] [Full Text]  
  • Wang, G., van Dam, A. P., Schwartz, I., Dankert, J. (1999). Molecular Typing of Borrelia burgdorferi Sensu Lato: Taxonomic, Epidemiological, and Clinical Implications. Clin. Microbiol. Rev. 12: 633-653 [Abstract] [Full Text]  
  • Gylfe, A., Olsen, B., Strasevicius, D., Marti Ras, N., Weihe, P., Noppa, L., Östberg, Y., Baranton, G., Bergström, S. (1999). Isolation of Lyme Disease Borrelia from Puffins (Fratercula arctica) and Seabird Ticks (Ixodes uriae) on the Faeroe Islands. J. Clin. Microbiol. 37: 890-896 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»