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Applied and Environmental Microbiology, September 1999, p. 4255-4260, Vol. 65, No. 9
Molecular Biology Branch (HFZ-113), Division
of Life Sciences, Office of Science and Technology, Center for Devices
and Radiological Health, Food and Drug Administration, Rockville,
Maryland
Received 22 February 1999/Accepted 9 June 1999
This study compared the activity of commercial liquid sterilants
and disinfectants on Bacillus subtilis spores deposited on three types of devices made of noncorrodible, corrodible, or polymeric material. Products like Renalin, Exspor, Wavicide-01, Cidexplus, and
cupric ascorbate were tested under conditions specified for liquid
sterilization. These products, at the shorter times indicated for
disinfection, and popular disinfectants, like Clorox, Cavicide, and
Lysol were also studied. Data obtained with a sensitive and quantitative test suggest that commercial liquid sterilants and disinfectants are less effective on contaminated surfaces than generally acknowledged.
0099-2240/99/$04.00+0
Bacterial Spores Survive Treatment with Commercial
Sterilants and Disinfectants
*
Corresponding author. Mailing address: Molecular
Biology Branch (HFZ-113), Center for Devices and Radiological Health,
Food and Drug Administration, 5600 Fishers Ln., Rockville, MD 20857. E-mail: JUS{at}CDRH.FDA.GOV.
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