This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hundt, K.
Right arrow Articles by Schauer, F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hundt, K.
Right arrow Articles by Schauer, F.
Agricola
Right arrow Articles by Hundt, K.
Right arrow Articles by Schauer, F.

 Previous Article  |  Next Article 

Applied and Environmental Microbiology, September 2000, p. 4157-4160, Vol. 66, No. 9
0099-2240/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Transformation of Triclosan by Trametes versicolor and Pycnoporus cinnabarinus

Kai Hundt,1,* Dierk Martin,2 Elke Hammer,1 Ulrike Jonas,1 Markus Karl Kindermann,3 and Frieder Schauer1

Institute of Microbiology and Molecular Biology1 and Institute of Chemistry and Biochemistry,3 Ernst-Moritz-Arndt-University, D-17487 Greifswald, and Südzucker AG Mannheim/Ochsenfurt, ZAFES, D-67283 Obrigheim,2 Germany

Received 2 March 2000/Accepted 15 June 2000

We investigated the ability of Trametes versicolor and Pycnoporous cinnabarinus to metabolize triclosan. T. versicolor produced three metabolites, 2-O-(2,4,4'-trichlorodiphenyl ether)-beta -D-xylopyranoside, 2-O-(2,4,4'-trichlorodiphenyl ether)-beta -D-glucopyranoside, and 2,4-dichlorophenol. P. cinnabarinus converted triclosan to 2,4,4'-trichloro-2'-methoxydiphenyl ether and the glucoside conjugate known from T. versicolor. The conjugates showed a distinctly lower cytotoxic and microbicidal activity than triclosan did.

* Corresponding author. Mailing address: Institute of Microbiology and Molecular Biology, Ernst-Moritz-Arndt-University of Greifswald, Friedrich-Ludwig-Jahn-Str. 15, D-17487 Greifwald, Germany. Phone: 49-(0)3834-864204. Fax: 49-(0)3834-864202. E-mail: kai.hundt{at}plasmaselect.com.

Applied and Environmental Microbiology, September 2000, p. 4157-4160, Vol. 66, No. 9
0099-2240/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Mima, T., Joshi, S., Gomez-Escalada, M., Schweizer, H. P. (2007). Identification and Characterization of TriABC-OpmH, a Triclosan Efflux Pump of Pseudomonas aeruginosa Requiring Two Membrane Fusion Proteins. J. Bacteriol. 189: 7600-7609 [Abstract] [Full Text]  
  • Teuten, E. L., Xu, L., Reddy, C. M. (2005). Two Abundant Bioaccumulated Halogenated Compounds Are Natural Products. Science 307: 917-920 [Abstract] [Full Text]  
  • Sietmann, R., Hammer, E., Specht, M., Cerniglia, C. E., Schauer, F. (2001). Novel Ring Cleavage Products in the Biotransformation of Biphenyl by the Yeast Trichosporon mucoides. Appl. Environ. Microbiol. 67: 4158-4165 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»