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Applied and Environmental Microbiology, April 2001, p. 1418-1422, Vol. 67, No. 4
0099-2240/01/$04.00+0   DOI: 10.1128/AEM.67.4.1418-1422.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Biological Activities and Structural Properties of the Atypical Bacteriocins Mesenterocin 52B and Leucocin B-TA33a

C. Corbier,1 F. Krier,2 G. Mulliert,1 B. Vitoux,1 and A.-M. Revol-Junelles2,*

Laboratoire de Cristallographie et Modélisation des Matériaux Minéraux et Biologiques, Groupe Biocristallographie, UPRESA CNRS 7036, Université Henri Poincaré-Nancy I, 54506 Vandoeuvre-lès-Nancy cedex,1 and Laboratoire de Bioprocédés Agro-Alimentaires, Ecole Nationale Supérieure d'Agronomie et des Industries Alimentaires---Institut National Polytechnique de Lorraine (ENSAIA-INPL), 54505 Vandoeuvre-lès-Nancy cedex,2 France

Received 27 July 2000/Accepted 17 January 2001

The antibacterial spectra and modes of action of synthetic peptides corresponding to mesenterocin 52B and leucocin B-TA33a greatly differ despite their high sequence homology. Circular dichroism experiments establish the capacity of each of these two peptides to partly fold into an amphiphilic helix that might be crucial for their adsorption at lipophilic-hydrophilic interfaces.


* Corresponding author. Mailing address: Laboratoire de Bioprocédés Agro-Alimentaires, Ecole Nationale Supérieure d'Agronomie et des Industries Alimentaires---Institut National Polytechnique de Lorraine (ENSAIA-INPL), 2, Avenue de la Forêt de Haye, 54505 Vandoeuvre-lès-Nancy cedex, France. Phone: 00 33 3 83 59 58 84. Fax: 00 33 3 83 59 58 04. E-mail: Anne-Marie.Revol{at}ensaia.inpl-nancy.fr.


Applied and Environmental Microbiology, April 2001, p. 1418-1422, Vol. 67, No. 4
0099-2240/01/$04.00+0   DOI: 10.1128/AEM.67.4.1418-1422.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.



This article has been cited by other articles:

  • Morisset, D., Berjeaud, J.-M., Marion, D., Lacombe, C., Frere, J. (2004). Mutational Analysis of Mesentericin Y105, an Anti-Listeria Bacteriocin, for Determination of Impact on Bactericidal Activity, In Vitro Secondary Structure, and Membrane Interaction. Appl. Environ. Microbiol. 70: 4672-4680 [Abstract] [Full Text]  
  • Limonet, M., Revol-Junelles, A.-M., Milliere, J.-B. (2002). Variations in the Membrane Fatty Acid Composition of Resistant or Susceptible Leuconostoc or Weissella Strains in the Presence or Absence of Mesenterocin 52A and Mesenterocin 52B Produced by Leuconostoc mesenteroides subsp. mesenteroides FR52. Appl. Environ. Microbiol. 68: 2910-2916 [Abstract] [Full Text]