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Applied and Environmental Microbiology, September 2002, p. 4642-4645, Vol. 68, No. 9
0099-2240/02/$04.00+0     DOI: 10.1128/AEM.68.9.4642-4645.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Effect of Weissella confusa Strain PL9001 on the Adherence and Growth of Helicobacter pylori

Hyeran Nam, Misun Ha, On Bae, and Yeonhee Lee*

Department of Biotechnology, Seoul Women's University, Seoul 139-774, Korea

Received 28 January 2002/ Accepted 18 June 2002

Viable and nonviable Weissella confusa strain PL9001 inhibited the binding of Helicobacter pylori to human gastric-cell line MKN-45 cells by more than 90%. Spent culture supernatant of PL9001 rapidly decreased the viability of H. pylori, rupturing cell walls. The results suggest that PL9001 is a probiotic that can reduce the infectivity and persistence of H. pylori.

* Corresponding author. Mailing address: Department of Biotechnology, Seoul Women's University, Seoul 139-774, Korea. Phone: 82-2-970-5664. Fax: 82-2-970-5669. E-mail: yhlee{at}swu.ac.kr.

Applied and Environmental Microbiology, September 2002, p. 4642-4645, Vol. 68, No. 9
0099-2240/02/$04.00+0     DOI: 10.1128/AEM.68.9.4642-4645.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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