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Applied and Environmental Microbiology, July 2003, p. 4278-4281, Vol. 69, No. 7
0099-2240/03/$08.00+0     DOI: 10.1128/AEM.69.7.4278-4281.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Mode of Bactericidal Action of Silver Zeolite and Its Comparison with That of Silver Nitrate

Yoshinobu Matsumura,1,2 Kuniaki Yoshikata,1 Shin-ichi Kunisaki,3 and Tetsuaki Tsuchido1,2*

Department of Biotechnology,1 High Technology Research Center, Kansai University, Suita 564-8680,2 Institute for Fundamental Research, Suntory, Ltd., Mishima-gun 618-8503, Osaka, Japan3

Received 2 December 2002/ Accepted 29 April 2003

The properties of the bactericidal action of silver zeolite as affected by inorganic salts and ion chelators were similar to those of silver nitrate. The results suggest that the contact of the bacterial cell with silver zeolite, the consequent transfer of silver ion to the cell, and the generation of reactive oxygen species in the cell are involved in the bactericidal activity of silver zeolite.

* Corresponding author. Mailing address: Department of Biotechnology, Faculty of Engineering, Kansai University, 3-3-35 Yamate-cho, Suita 564-8680, Osaka, Japan. Phone: 81-6-6368-0880. Fax: 81-6-6388-8609. E-mail: ttsuchi{at}ipcku.kansai-u.ac.jp.

Applied and Environmental Microbiology, July 2003, p. 4278-4281, Vol. 69, No. 7
0099-2240/03/$08.00+0     DOI: 10.1128/AEM.69.7.4278-4281.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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