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Applied and Environmental Microbiology, October 2004, p. 6306-6308, Vol. 70, No. 10
0099-2240/04/$08.00+0     DOI: 10.1128/AEM.70.10.6306-6308.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

SHORT REPORT

Intestinal Mucus Alters the Ability of Probiotic Bacteria To Bind Aflatoxin B1 In Vitro

S. Gratz,1,2 H. Mykkänen,1 A. C. Ouwehand,3,4 R. Juvonen,5 S. Salminen,3 and H. El-Nezami1,2*

Department of Clinical Nutrition,1 Food and Health Research Centre,2 Department of Pharmacology and Toxicology, University of Kuopio, Kuopio,5 Department of Biochemistry and Food Chemistry, University of Turku, Turku,3 Danicso Innovations, Kantvik, Finland4

Received 1 February 2004/ Accepted 20 June 2004

ABSTRACT

Several probiotics are known to bind aflatoxin B1 (AFB1) to their surfaces and to adhere to intestinal mucus. In this study, preincubation of two probiotic preparations with either AFB1 or mucus reduced the subsequent surface binding of mucus and AFB1, respectively, in a strain-dependent manner.

* Corresponding author. Present address: Department of Clinical Nutrition, University of Kuopio, Harjulantie 1, P.O. Box 1627, 70211 Kuopio, Finland. Phone: 358-17 163615. Fax: 358-17 162792. E-mail: silvia.gratz{at}uku.fi.

Applied and Environmental Microbiology, October 2004, p. 6306-6308, Vol. 70, No. 10
0099-2240/04/$08.00+0     DOI: 10.1128/AEM.70.10.6306-6308.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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