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Applied and Environmental Microbiology, November 2004, p. 6931-6935, Vol. 70, No. 11
0099-2240/04/$08.00+0     DOI: 10.1128/AEM.70.11.6931-6935.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

SHORT REPORT

Diversity of Toxic Shock Syndrome Toxin 1-Positive Staphylococcus aureus Isolates

John E. Warner* and Andrew B. Onderdonk

Channing Laboratory, Departments of Pathology and Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts

Received 8 March 2004/ Accepted 8 July 2004

ABSTRACT

Staphylococcus aureus isolates from women with nasal, anal, or vaginal colonization were evaluated for population diversity by pulsed-field gel electrophoresis. Cluster analysis of restriction patterns revealed diversity indices of 0.89 and 0.99 for toxic shock syndrome toxin 1-positive and -negative isolates, respectively. Toxin-producing strains were isolated more frequently from the nares than from other sites.


* Corresponding author. Mailing address: Channing Laboratory Department of Pathology and Medicine, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Ave., Boston, MA 02115 Phone: (617) 525-2528. Fax: (617) 731-1541. E-mail: jwarner{at}rics.bwh.harvard.edu.


Applied and Environmental Microbiology, November 2004, p. 6931-6935, Vol. 70, No. 11
0099-2240/04/$08.00+0     DOI: 10.1128/AEM.70.11.6931-6935.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.