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Applied and Environmental Microbiology, April 2004, p. 2560-2565, Vol. 70, No. 4
0099-2240/04/$08.00+0     DOI: 10.1128/AEM.70.4.2560-2565.2003
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Antibiotic Production by a Roseobacter Clade-Affiliated Species from the German Wadden Sea and Its Antagonistic Effects on Indigenous Isolates

Institute for Chemistry and Biology of the Marine Environment, University of Oldenburg, D-26111 Oldenburg,¹ Institute for Organic Chemistry, University of Göttingen, D-37077 Göttingen,² FB Naturwissenschaft und Technik, University of Applied Sciences Ostfriesland, D-26723 Emden, Germany³

Received 30 September 2003/ Accepted 14 January 2004

A strain affiliated with the Roseobacter clade and producing a new antibiotic named tropodithietic acid (L. Liang, Ph.D. thesis, University of Göttingen, Göttingen, Germany, 2003) was isolated from the German Wadden Sea. The compound showed strong inhibiting properties with respect to marine bacteria of various taxa and marine algae. Antibiotic production was found to occur during the complete growth phase. Strain mutants without antagonistic properties appeared several times spontaneously.

We dedicate this paper to Prof. Dr. Axel Zeeck on the occasion of his 65th birthday.

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