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Applied and Environmental Microbiology, September 2004, p. 5682-5684, Vol. 70, No. 9
0099-2240/04/$08.00+0     DOI: 10.1128/AEM.70.9.5682-5684.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

SHORT REPORT

Effect of Escherichia coli Morphogene bolA on Biofilms

Helena L. A. Vieira, Patrick Freire, and Cecília M. Arraiano*

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal

Received 28 January 2004/ Accepted 28 April 2004

ABSTRACT

Biofilm physiology is established under a low growth rate. The morphogene bolA is mostly expressed under stress conditions or in stationary phase, suggesting that bolA could be implicated in biofilm development. In order to verify this hypothesis, we tested the effect of bolA on biofilm formation. Overexpression of bolA induces biofilm development, while bolA deletion decreases biofilms.

* Corresponding author. Mailing address: Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, 2781-901 Oeiras, Portugal. Phone: 351 214 469 547. Fax: 351 214 411 277. E-mail: cecilia{at}itqb.unl.pt.

Applied and Environmental Microbiology, September 2004, p. 5682-5684, Vol. 70, No. 9
0099-2240/04/$08.00+0     DOI: 10.1128/AEM.70.9.5682-5684.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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