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Applied and Environmental Microbiology, January 2005, p. 550-553, Vol. 71, No. 1
0099-2240/05/$08.00+0     doi:10.1128/AEM.71.1.550-553.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Byssochlamys nivea as a Source of Mycophenolic Acid

Olivier Puel,1* Souria Tadrist,1 Pierre Galtier,1 Isabelle P. Oswald,1 and Marcel Delaforge2

Laboratoire de Pharmacologie-Toxicologie, Institut National de Recherche Agronomique, Toulouse,1 CNRS URA 2096, CEA Saclay DSV/DRM/SPI, Gif sur Yvette, France2

Received 22 April 2004/ Accepted 26 August 2004

Byssochlamys species are responsible for spoilage and degradation of fruits and silages and can also produce the mycotoxin patulin. We analyzed secondary metabolite production by Byssochlamys nivea. Mycophenolic acid and its precursors, 5-methylorsellinic acid and 5,7-dihydroxy-4-methylphthalide, were identified in all of the B. nivea strains that we examined.

* Corresponding author. Mailing address: Laboratoire de Pharmacologie-Toxicologie, Institut National de la Recherche Agronomique, 180 chemin de Tournefeuille, 31931 Toulouse Cedex 9, France. Phone: 33 561 285154. Fax: 33 561 285310. E-mail: opuel{at}toulouse.inra.fr.

Applied and Environmental Microbiology, January 2005, p. 550-553, Vol. 71, No. 1
0099-2240/05/$08.00+0     doi:10.1128/AEM.71.1.550-553.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.





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Copyright © 2005 by the American Society for Microbiology. All rights reserved.