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Applied and Environmental Microbiology, January 2005, p. 594-596, Vol. 71, No. 1
0099-2240/05/$08.00+0     doi:10.1128/AEM.71.1.594-596.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Novel Keratinase from Bacillus subtilis S14 Exhibiting Remarkable Dehairing Capabilities

Alexandre J. Macedo,1,{dagger} Walter O. Beys da Silva,1 Renata Gava,1 David Driemeier,2 João Antonio Pêgas Henriques,1,3 and Carlos Termignoni1,4*

Centro de Biotecnologia do Estado do Rio Grande do Sul,1 Faculdade de Veterinária,2 Departamento de Biofísica,3 Departamento de Bioquímica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil4

Received 9 July 2004/ Accepted 5 August 2004

We report the isolation of a keratinolytic-producing Bacillus subtilis strain and the characterization of the exceptional dehairing properties of its subtilisin-like keratinase. This enzyme can be an alternative to sodium sulfide, the major pollutant from tanneries, and may completely replace it. Its unique nonactivity upon collagen enhances its industrial potential.

* Corresponding author. Mailing address: Av. Bento Goncalves, 9000, Cx. Postal 15005, CEP 90501-970, Porto Alegre RS, Brazil. Phone: 55 51 316 6092. Fax: 55 51 3316 7309. E-mail: ctermignoni{at}cbiot.ufrgs.br.

{dagger} Present address: German Research Centre for Biotechnology (GBF), 38124 Braunschweig, Germany.

Applied and Environmental Microbiology, January 2005, p. 594-596, Vol. 71, No. 1
0099-2240/05/$08.00+0     doi:10.1128/AEM.71.1.594-596.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.





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