This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by van Tongeren, S. P.
Right arrow Articles by Welling, G. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by van Tongeren, S. P.
Right arrow Articles by Welling, G. W.
Agricola
Right arrow Articles by van Tongeren, S. P.
Right arrow Articles by Welling, G. W.

 Previous Article  |  Next Article 

Applied and Environmental Microbiology, October 2005, p. 6438-6442, Vol. 71, No. 10
0099-2240/05/$08.00+0     doi:10.1128/AEM.71.10.6438-6442.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

SHORT REPORT

Fecal Microbiota Composition and Frailty

Sandra P. van Tongeren,1 Joris P. J. Slaets,2 H. J. M. Harmsen,1 and Gjalt W. Welling1*

Department of Medical Microbiology,1 Department of Geriatrics, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands2

Received 17 February 2005/ Accepted 2 June 2005

The relationship between fecal microbiota composition and frailty in the elderly was studied. Fecal samples from volunteers with high frailty scores showed a significant reduction in the number of lactobacilli (26-fold). At much higher population levels, both the Bacteroides/Prevotella (threefold) and the Faecalibacterium prausnitzii (fourfold) groups showed a significant reduction in percentage of total number of hybridizable bacteria in the elderly with high frailty scores. In contrast to this, the number of Enterobacteriaceae was significantly higher (sevenfold) in samples from very frail volunteers.

* Corresponding author. Mailing address: Department of Medical Microbiology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Phone: 31 50 3633513. Fax: 31 503633528. E-mail: g.w.welling{at}med.umcg.nl.

Applied and Environmental Microbiology, October 2005, p. 6438-6442, Vol. 71, No. 10
0099-2240/05/$08.00+0     doi:10.1128/AEM.71.10.6438-6442.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Turroni, F., Foroni, E., Pizzetti, P., Giubellini, V., Ribbera, A., Merusi, P., Cagnasso, P., Bizzarri, B., de'Angelis, G. L., Shanahan, F., van Sinderen, D., Ventura, M. (2009). Exploring the Diversity of the Bifidobacterial Population in the Human Intestinal Tract. Appl. Environ. Microbiol. 75: 1534-1545 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»