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Applied and Environmental Microbiology, December 2005, p. 8978-8981, Vol. 71, No. 12
0099-2240/05/$08.00+0     doi:10.1128/AEM.71.12.8978-8981.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

SHORT REPORT

Growth and Multiplexed Analysis of Microorganisms on a Subdivided, Highly Porous, Inorganic Chip Manufactured from Anopore

Colin J. Ingham,1,3* Maaike van den Ende,1 Dirk Pijnenburg,2 Peter C. Wever,1 and Peter M. Schneeberger1

Department of Medical Microbiology and Infection Control, Hospital Jeroen Bosch, Nieuwstraat 34, 5211 NL 's-Hertogenbosch, The Netherlands,1 PamGene International B.V., Nieuwstraat 30, 5211 NL 's-Hertogenbosch, The Netherlands,2 Laboratory of Microbiology, Wageningen University, Hesselink van Suchtelenweg 4, NL-6703 CT Wageningen, The Netherlands3

Received 15 July 2005/ Accepted 14 September 2005

A highly porous inorganic material (Anopore) was shown to be an effective support for culturing and imaging a wide range of microorganisms. An inert barrier grid was printed on the rigid surface of Anopore to create a "living chip" of 336 miniaturized compartments (200/cm2) with broad applications in microbial culture.

* Corresponding author. Mailing address: Department of Medical Microbiology and Infection Control, Hospital Jeroen Bosch, Nieuwstraat 34, 5211 NL 's-Hertogenbosch, The Netherlands. Phone: 31 0 73 6992875. Fax: 31 73 6162958. E-mail: cingham2{at}mac.com.

Applied and Environmental Microbiology, December 2005, p. 8978-8981, Vol. 71, No. 12
0099-2240/05/$08.00+0     doi:10.1128/AEM.71.12.8978-8981.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



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