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Applied and Environmental Microbiology, May 2005, p. 2753-2755, Vol. 71, No. 5
0099-2240/05/$08.00+0     doi:10.1128/AEM.71.5.2753-2755.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

SHORT REPORT

Dose Determination for Acute Salmonella Infection in Pigs

A. T. Loynachan1,2 and D. L. Harris2,3*

Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University,1 Department of Animal Science, College of Agriculture, Iowa State University,2 Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa3

Received 1 June 2004/ Accepted 23 November 2004

Pigs were exposed to various levels of Salmonella enterica subsp. enterica serovar Typhimurium by either intranasal inoculation or by subjecting them to a contaminated environment. More than 103 salmonellae were required to induce acute Salmonella infection. These results indicate that intervention against acute Salmonella infection in lairage may be more readily achieved than previously thought.

* Corresponding author. Mailing address: Iowa State University, Department of Animal Science, Room 11, Kildee Hall, Ames, IA 50011. Phone: (515) 294-1664. Fax: (515) 294-5294. E-mail: hharris{at}iastate.edu.

Applied and Environmental Microbiology, May 2005, p. 2753-2755, Vol. 71, No. 5
0099-2240/05/$08.00+0     doi:10.1128/AEM.71.5.2753-2755.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Boyen, F, Pasmans, F, Van Immerseel, F, Donne, E, Morgan, E, Ducatelle, R, Haesebrouck, F (2009). Porcine in vitro and in vivo models to assess the virulence of Salmonella enterica serovar Typhimurium for pigs. Lab Anim 43: 46-52 [Abstract] [Full Text]  


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