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Applied and Environmental Microbiology, June 2005, p. 3126-3130, Vol. 71, No. 6
0099-2240/05/$08.00+0     doi:10.1128/AEM.71.6.3126-3130.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Genomic Islands in the Corynebacterium efficiens Genome

Ren Zhang1 and Chun-Ting Zhang2*

Department of Epidemiology and Biostatistics, Tianjin Cancer Institute and Hospital, Tianjin 300060, China,1 Department of Physics, Tianjin University, Tianjin 300072, China2

Received 19 November 2004/ Accepted 21 December 2004

Corynebacterium efficiens is a gram-positive nonpathogenic bacterium which can grow and produce glutamate at 40°C or above. By using the cumulative GC profile method, we have identified four genomic islands which have many unifying genomic island-specific features in the C. efficiens genome. The presence of the gene encoding an aspartate kinase in a genomic island helps explain the unexpected low thermal stability of this enzyme; i.e., the adaptive mutations have not occurred extensively due to the recent horizontal gene transfer.

* Corresponding author. Mailing address: Department of Physics, Tianjin University, Tianjin 300072, China. Phone: 86-22-2740-2987. Fax: 86-22-2740-2697. E-mail: ctzhang{at}tju.edu.cn.

Applied and Environmental Microbiology, June 2005, p. 3126-3130, Vol. 71, No. 6
0099-2240/05/$08.00+0     doi:10.1128/AEM.71.6.3126-3130.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

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