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Applied and Environmental Microbiology, January 2006, p. 953-955, Vol. 72, No. 1
0099-2240/06/$08.00+0     doi:10.1128/AEM.72.1.953-955.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

HacA-Independent Induction of Chaperone-Encoding Gene bipA in Aspergillus niger Strains Overproducing Membrane Proteins

Anoushka Davé ,1,{dagger} David J. Jeenes,1 Donald A. Mackenzie,1 and David B. Archer2*

Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA,1 School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom2

Received 9 August 2005/ Accepted 6 October 2005

Transcription of two unfolded protein response genes, hacA and bipA, was examined in Aspergillus niger strains overproducing membrane proteins. Despite elevated bipA mRNA levels, no 5'-truncated hacA transcript was detected, raising the possibility of a hacA-independent induction of bipA mRNA under the stress of membrane protein overproduction in A. niger.

* Corresponding author. Mailing address: School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom. Phone: 44-115-951-3313. Fax: 44-115-951-3251. E-mail: david.archer{at}nottingham.ac.uk

{dagger} Present address: Radiation and Genomic Stability Unit, Medical Research Council, Harwell, Didcot, Oxfordshire OX11 7NG, United Kingdom.

Applied and Environmental Microbiology, January 2006, p. 953-955, Vol. 72, No. 1
0099-2240/06/$08.00+0     doi:10.1128/AEM.72.1.953-955.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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