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Applied and Environmental Microbiology, November 2006, p. 7377-7379, Vol. 72, No. 11
0099-2240/06/$08.00+0 doi:10.1128/AEM.00486-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.
Molecular Analysis of tet(W) Gene-Mediated Tetracycline Resistance in Dominant Intestinal Bifidobacterium Species from Healthy Humans
Ana Belén Flórez,
Mohammed Salim Ammor,
Pablo Álvarez-Martín,
Abelardo Margolles, and
Baltasar Mayo*
Instituto de Productos Lácteos de Asturias (CSIC), Carretera de Infiesto s/n, 33300-Villaviciosa, Asturias, Spain
Received 28 February 2006/
Accepted 19 August 2006
tet(W) was found responsible for tetracycline resistance (MICs, 4 to
32 µg ml1) in dominant bifidobacterial species from the gastrointestinal tracts of healthy humans. The gene from Bifidobacterium longum H66 proved to be identical over a 2.6-kbp region to the recently described tet(W) determinant of Butyrivibrio fibrisolvens.
* Corresponding author. Mailing address: Instituto de Productos Lácteos de Asturias (CSIC), Carretera de Infiesto s/n, 33300-Villaviciosa, Asturias, Spain. Phone: 34 985 89 21 31. Fax: 34 985 89 22 33. E-mail:
baltasar.mayo{at}ipla.csic.es.
Published ahead of print on 25 August 2006.
Applied and Environmental Microbiology, November 2006, p. 7377-7379, Vol. 72, No. 11
0099-2240/06/$08.00+0 doi:10.1128/AEM.00486-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.
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