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Applied and Environmental Microbiology, March 2006, p. 2231-2234, Vol. 72, No. 3
0099-2240/06/$08.00+0     doi:10.1128/AEM.72.3.2231-2234.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

SHORT REPORT

Tolerance of Listeria monocytogenes to Cell Envelope-Acting Antimicrobial Agents Is Dependent on SigB

Máire Begley,1,2 Colin Hill,1,2* and R. Paul Ross2,3

Department of Microbiology,1 Alimentary Pharmabiotic Centre, University College Cork, Cork,2 Teagasc Dairy Products Research Centre, Moorepark, Fermoy, County Cork, Ireland3

Received 2 September 2005/ Accepted 26 December 2005

Mutation of sigB impairs the ability of Listeria monocytogenes to grow in sublethal levels, and to survive in lethal concentrations, of the bacteriocins nisin and lacticin 3147 and the antibiotics ampicillin and penicillin G. SigB may therefore represent an attractive target for the development of new control and treatment strategies for this important pathogen.

* Corresponding author. Mailing address: Department of Microbiology and Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland. Phone: 353-21-4903173. Fax: 353-21-4901373. E-mail: c.hill{at}ucc.ie.

Applied and Environmental Microbiology, March 2006, p. 2231-2234, Vol. 72, No. 3
0099-2240/06/$08.00+0     doi:10.1128/AEM.72.3.2231-2234.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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