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Applied and Environmental Microbiology, September 2007, p. 5648-5652, Vol. 73, No. 17
0099-2240/07/$08.00+0     doi:10.1128/AEM.00052-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Regulation of the mpt Operon in Listeria innocua by the ManR Protein{triangledown}

Junfeng Xue and Kurt W. Miller*

Department of Molecular Biology, University of Wyoming, Laramie, Wyoming 82071

Received 9 January 2007/ Accepted 24 June 2007

The phosphotransferase system regulation domain (PRD)-containing activator, ManR, is required for glucose-controlled transcription of the mannose permease two (mpt) operon in Listeria innocua. His-871 in ManR PRD-II is needed for mpt repression in glucose-free media. His-506 in PRD-I is needed for mpt induction by glucose.

* Corresponding author. Mailing address: Department of Molecular Biology, University of Wyoming, 1000 E. University Avenue, Dept. 3944, Laramie, WY 82071-3944. Phone: (307) 766-2037. Fax: (307) 766-5098. E-mail: kwmiller{at}uwyo.edu

{triangledown} Published ahead of print on 6 July 2007.

Applied and Environmental Microbiology, September 2007, p. 5648-5652, Vol. 73, No. 17
0099-2240/07/$08.00+0     doi:10.1128/AEM.00052-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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