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Applied and Environmental Microbiology, December 2007, p. 7763-7766, Vol. 73, No. 23
0099-2240/07/$08.00+0     doi:10.1128/AEM.01818-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Ubericin A, a Class IIa Bacteriocin Produced by Streptococcus uberis{triangledown} ,{dagger}

Nicholas C. K. Heng,* Grace A. Burtenshaw, Ralph W. Jack, and John R. Tagg

Department of Microbiology and Immunology, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand

Received 5 August 2007/ Accepted 5 October 2007

Streptococcus uberis, a causal agent of bovine mastitis, produces ubericin A, a 5.3-kDa class IIa (pediocin-like) bacteriocin, which was purified and characterized. The uba locus comprises two overlapping genes: ubaA (ubericin A precursor peptide) and ubaI (putative immunity protein). Ubericin A is the first streptococcal class IIa bacteriocin to be characterized.

* Corresponding author. Present address: Department of Oral Sciences, Faculty of Dentistry, University of Otago, P.O. Box 647, Dunedin 9054, New Zealand. Phone: 64 3 479-5290. Fax: 64 3 479-7078. E-mail: nicholas.heng{at}stonebow.otago.ac.nz

{triangledown} Published ahead of print on 12 October 2007.

{dagger} Supplemental material for this article may be found at http://aem.asm.org/.

Applied and Environmental Microbiology, December 2007, p. 7763-7766, Vol. 73, No. 23
0099-2240/07/$08.00+0     doi:10.1128/AEM.01818-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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